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Targeting the integrated methylation-metabolism-immunity axis is promising but requires better delivery systems and toxicity management

Mol Psychiatry (2009) 14(696704):647.10.1038/mp.2008.26 263 GiganteADBondDJLaferBLamRWYoungLTYathamLN

Without adequate levels of ALA, these enzymatic reactions stall, leading to a severe bottleneck in cellular energy production and an accumulation of metabolic byproducts like lactic acid